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Cologne, the fourth-largest city in Germany is located on both sides of the Rhine River with a population of around 1.02 million. In medieval times it was the largest city of the Holy Roman Empire. It is one of the nation's media, tourism and business hotspots. More than 60 financial institutions are represented in Cologne. One of these is the Sparkasse Köln Bonn founded over 170 years ago; it is Cologne's largest financial institution and one of the largest savings banks in Germany. Cologne is one of the leading centres for the European automotive industry Cologne is one of the warmest cities in Germany and has a temperate–oceanic climate with cool winters and warm summers.
Bayer HealthCare Pharmaceuticals located in Cologne markets its products in more than 100 countries, and in 2012 generated sales of €10,803 million. The BioCampus Cologne is developing into a motor of innovation and one of the largest pharmaceutical and biotech parks in Germany.
Figure 1: Turn over in Top pharmaceutical companies
In Cologne,Rigontec company is the leader in RIG-I targeting RNA therapeutics. The company has raised €14.25 million recently. Distributable profit of Bayer, the pharmaceutical giant in Germany is 2067 euro million in 2015 alone and is leading ahead in immune products.
Figure 2: Research on Immunological products
University of Cologne includes department for neurosciences with collaborative interactions of Cologne‘s Neuroscience Research groups. The Alzheimer Forschung Initiative e.V. grants funds for research on brain sciences mainly Alzheimer’s. It grants maximum of € 80,000 for two years. The German Research Foundation provides funds for research in (Cellular Stress Responses in Aging-Associated Diseases) cluster at University of Cologne. The total funding amounts to about 120 million euros over the next five years.
Figure 3: Global funding for neuroscience research
In Europe, the other major hub for biopharmaceutical CMOs, 20 CMOs have facilities located in Germany majorly working on vaccines. The Lonza Company, most-trusted suppliers to the Pharma & Biotech generated sales of CHF 3.8 billion in 2015in vaccine products. Delta-Vir GmbH is expanding the access of novel therapeutic cancer vaccine treatment in Cologne. It has developed dendritic cell vaccine work which is effective. It also developed DVG01 vaccine to treat patients with Glioblastoma multiforme with the global market around 2.58 billion euros ($3.39 billion).
Figure 4: Global research on vaccines (%)
The current focus of research worldwide is Oncology. Universities in cologne have been extensively conducting research on cancer biology. Global spending on oncology medicines increased 10.3% in 2014 and reached $100 billion from $75 billion.
Figure 5: Research activities in cancer biology(%)
ChemCologne, Europe’s strongest chemical region generated 30.5 billion euro in the chemical industry in 2015 which is equivalent to 22% of Germany's total chemical turnover. German mechanical engineering has always been the backbone of the German economy. Over 11% of German R&D expenditure is in automotive manufacturing industry and average euro 35 bn p.a cumulative direct investments in overseas. The turnover is EUR 200 bn per annum with 11% of world machinery production. The products have 16 % of global machinery exports.
Figure 6: Worldwide employment in engineering sector
The global market for interventional cardiology technologies reached an estimated $12.2 billion in 2014. According to a new study by Smithers Apex– it will grow to $22.5 billion (€20.9 billion) by 2021, with a year-on-year increase of 9.1%. Different projects in University of Cologne are funded by EU grants programmes like funding support of 11.9 M€ for 5.5 years for project on Embryonic Stem cell-based Novel Alternative Testing Strategies.
Figure 7: Research on cardiovascular diseases
The Max Planck-Genome-centre Cologne (MP-GC) is a core facility for Max Planck Institutes performing next generation sequencing (NGS) and raises funds for various projects. The Federal Ministry of Research and Education is providing support of 60 million euros for five years in order to establish industrial biotechnology clusters as part of BioIndustries 2021 competition and from the private sector, research and development projects are expected to benefit from funding of 150 million euros.
CLIB- Cluster Industrial Biotechnology
IBP- Industrial Processes with Biogenous Building Blocks and Performance Proteins
Figure 8: Funding in Biotech sector
Cologne has a distinguished and high-calibre research and academic community in the fields of medicine and biotechnology. There are over 20 companies in the municipality and over 40 in the region as a whole working in the biotechnology sector alone, Cologne is a best example of emerging destination for students and researchers. It is also the most popular tourist attraction with high rise structures, museums and carnival.
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Tourist Attractions in Cologne | Cologne Conferences
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Islamic Azad University, Iran
Title:Reproduction Carangoides chrysophrys in Persian Gulf (Hormozgan Province Waters)
United Medical & Dental College, Pakistan
Central Veterinary Laboratory, Agriculture & Marine Resources Affairs, Bahrain
Title:Incidence of pigeon’s infectious coryza in a farm in Bahrain and the associated risk factors
Airlangga University, Indonesia
Title:Correlation between benzene concentrations with trans and trans-muconic acid
King Saud University, Saudi Arabia
Title:The impact of appropriate assessment of pressure ulcer among clinicians
King Saud University, Saudi Arabia
Title:The effect of educational program on nurses’ knowledge about pressure ulcer
Edna Adan University, Somaliland
University of Surrey, UK
The Public Authority for Applied Education and Training (PAAET), Kuwait
The Public Authority for Applied Education and Training (PAAET), Kuwait
Title:Performance enhancement of tubular membrane module using air bubbling system
Central Metallurgical Research & Development Institute, Egypt
Title:Modal finite element analysis of the first global body in white Saudi car Gazal 1
The University of Manchester, UK
The University of Manchester, UK
Title:Enhanced PIM-1 membrane performance using OA-GO-UiO-66 filler for CO2 separation
King Faisal University, Saudi Arabia
Institute of Radiological Protection and Nuclear Safety, France
Title:Stem cell therapy for the treatment of severe tissue damage after radiation exposure
Shahed University, Iran
University of Tehran, Iran
University of Tehran, Iran
University of Tehran, Iran
University of Tehran, Iran
Texas A&M University, USA
Title:Dairy manure gasification for heat and power generation
Taif University, Saudi Arabia
Title:Development and evaluation of chitosan-based systems for oral delivery of insulin
Taif University, Saudi Arabia
Title:Development and evaluation of chitosan-based systems for oral delivery of insulin
Jhang (sub-campus University of Veterinary and Animal Sciences, Lahore) PunjabPakistan
Islamic Azad University, Iran
Title:The effect of amino acid supplement on the efficacy of the Newcastle vaccine in broiler poultries
Islamic Azad University, Iran
Islamic Azad University, Iran
National Center for Scientific Research “Demokritosâ€, Greece
University of Education Freiburg, Germany
Hirszfeld Institute of Immunology and Experimental Therapy, Iran
Institute of Pharmacology- PAS, Poland
Alabama A&M University, USA
Title:Standoff Raman detection of economically motivated adulteration in food
Latrobe University, Australia
State Office for Inventions and Trademarks, Romania
Title:A theoretic model of astro-particles forming from a Bose-Einstein condensate of gammons or mesons
Scientific-Technological Center of Organic and Pharmaceutic Chemistry, Armenia
Title:Polymerization in Monomer - Water Heterogeneous Systems
National Academy of Sciences of Republic of Armenia, Armenia
Title:Growing profi le of single crystals using polymer materials
Institute for Physical Research, Republic of Armenia
Ibrahim Medical College, Bangladesh
Title:Relationship of dental diseases with systemic diseases and its managements
Taif University, KSA
Title:Hemoglobin derivatives concentration enhacement after usage of magnetic treated water (MTW)
International Institute of Tropical Agriculture, Nigeria
Clinical Sciences Bayer, China
Osong Medical Innovation Foundation, South Korea
Title:A case of surgical repair of fracture of the tibia in a common marmoset (Callithrix jacchus)
Beykent University, Turkey
Title:Exhaust Gas Heat-Driven Steam Ejector Refrigeration for an Automobile
The Education University of Hong Kong, China
Faculty of Design and Environment, Technological and Higher Education Institute of Hong Kong
Title:Capabilities of planted groundcovers in promoting sustainability of revegetated soil slopes
Chuan Sheng Dental Clinic, Taiwan